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QSB Seminar Series 291 (1/27/17)

Date: 
January 27, 2017 - 12:00pm

Dr. Lanning, California State University, Los Angeles

Abstract:

Mitochondrial dysfunction is associated with many pathologies including cancer, neurodegenerative diseases, cardiovascular disease, and mitochondrial diseases. However, in many cases, the distinct mechanisms by which mitochondrial dysfunction promotes these diseases remain unknown, and up to 20% of the mitochondrial proteome remains functionally uncharacterized. We screened ~1,000 mitochondrial proteins for their contributions to maintaining cellular energy homeostasis, and identified a mitochondrial adenylate kinase which significantly regulates ATP levels, AMPK/mTOR signaling, and cellular redox homeostasis.

Flyer File

Location

Location: 
Classroom and Office Building 2 170

Contact Information

Name: 
Fabian Filipp
Title: 
Assistant Professor
Department: 
School of Natural Sciences
Address: 
5200 North Lake Rd.
Merced, CA 95343
United States
Address: 
5200 North Lake Rd.
Merced, CA 95343
United States