The Wolf lab studies the genetic and neural circuit mechanisms for coding simple behaviors, including motivated seeking and plasticity driven by addictive drugs. We also study the regulation of DNA damage repair.
Mef2 induction of the immediate early gene Hr38/Nr4a is terminated by Sirt1 to promote ethanol tolerance. Adhikari P, Orozco D, Randhawa H, Wolf FW. Genes Brain Behav. 2019 Mar;18(3):e12486. doi: 10.1111/gbb.12486. Epub 2018 May 28.
Satiation state-dependent dopaminergic control of foraging in Drosophila. Landayan D, Feldman DS, Wolf FW. Sci Rep. 2018 Apr 10;8(1):5777. doi: 10.1038/s41598-018-24217-1.
Perineurial Barrier Glia Physically Respond to Alcohol in an Akap200-Dependent Manner to Promote Tolerance. Parkhurst SJ, Adhikari P, Navarrete JS, Legendre A, Manansala M, Wolf FW. Cell Rep. 2018 Feb 13;22(7):1647-1656. doi: 10.1016/j.celrep.2018.01.049.