Professor Ortiz's research focuses on the regulation of kidney function and metabolism in a variety of animal models, including seals and dolphins, with the intent that the data will have translative value to clinical medicine. These studies are conducted in collaboration with colleagues at:
- Sonoma State University
- University of Alaska, Fairbanks
- University of California, Santa Cruz
His lab - in conjunction with collaborators at Kagawa Medical University, SUNY Buffalo Medical School, and Tulane University HSC - investigate:
- Role of aldosterone plays in exacerbating high blood pressure
- Effects of aldosterone antagonism and hypercholesterolemia on renal sodium regulation
Professor Ortiz is also pursuing studies that address the link between diabetes and obesity with hypertension.
From an evolutionary perspective, he is interested in the physiological mechanisms marine-adapted vertebrates use to regulate water and electrolytes during a variety of altered environmental conditions, such as prolonged food deprivation or extended fresh water exposure.