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Biochemistry and Molecular Biology

David Ardell David Ardell
Associate Professor, Molecular & Cell Biology

Computational biology of gene expression systems, including:

  • Structure, function, evolution and coevolution with genomes
  • Functional and evolutionary bioinformatics of RNA and proteins
  • Evolutionary and comparative genomics
 

 

dardell@ucmerced.edu
(209) 228-2953
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Patricia LiWang Patricia LiWang
Professor, Molecular & Cell Biology
  • Biochemistry and biophysics
  • Structural biology of chemokines
  • Applications to HIV and inflammatory diseases
pliwang@ucmerced.edu
(209) 228-4568
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Nestor Oviedo Nestor Oviedo
Professor, Molecular & Cell Biology
  • Tissue regeneration
  • Stem cells
  • Cancer
  • Planarian biology
noviedo2@ucmerced.edu
(209) 228-4541
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Axel Visel Axel Visel
Adjunct Professor, Molecular & Cell Biology
avisel@ucmerced.edu
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Zhong Wang Zhong Wang
Adjunct Professor, Molecular & Cell Biology
zwang37@ucmerced.edu
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Maria-Elena Zoghbi Maria-Elena Zoghbi
Associate Professor, Molecular & Cell Biology
mzoghbi@ucmerced.edu
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Chris Amemiya Chris Amemiya
Professor, Molecular & Cell Biology
camemiya@ucmerced.edu
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Xuecai Ge Xuecai Ge
Associate Professor, Molecular & Cell Biology

We study mechanisms of cell signaling in the developing brain, focusing on primary cilium, the antenna-like organelle that integrate signaling pathways in the cell. Our research aims to shed light on how signaling errors lead to brain developmental disorders.

Publications:

Ge X*, Yang H, Bednarek MA, Galon-Tilleman H, Chen P, Chen M, Lichtman JS, Wang Y, Dalmas O, Yin Y, Tian H, Jermutus L, Grimsby J, Rondinone, CM, Konkar A, Kaplan, DD. (2018) LEAP2 is an endogenous Antagonist of the Ghrelin Receptor. Cell Metabolism. 27(2): 461-469. doi: 10.1016/j.cmet.2017.10.01 *Author of correspondence.

Ge X, Milenkovic L, Suyama K, Hartl T, Winan A, Meyer T, Scott MP. (2015) Integration of Neuropilin with Hedgehog signal transduction through control of Phosphodiesterase 4 and protein kinase A. eLife. 4:e07068. DOI: 10.7554/eLife.07068.

Ge X, Frank CL, Calderon de Anda F, Tsai LH. (2010) Hook3 and PCM1 regulate neurogenesis by controlling the centrosome dynamics and interkinetic nuclear migration. Neuron 65:191-203

xge2@ucmerced.edu
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Ramen Saha Ramen Saha
Associate Professor, Molecular & Cell Biology

Epigenetic mechanisms of neuronal gene transcription and their role in mental health.

rsaha3@ucmerced.edu
(209) 228-2425
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Clarissa Nobile Clarissa Nobile
Professor, Molecular & Cell Biology

Professor Nobile's research is directed toward understanding the molecular and mechanistic basis of microbial communities. Her lab is interested in investigating how transcriptional networks underlie the regulation of gene expression during biofilm development. Much of this work is carried out in the species Candida albicans, the most prevalent fungal pathogen of humans. The lab is also beginning to study interspecies interactions between different fungal and bacterial species. Questions that the lab is currently pursuing include: How are microbial communities regulated? How are microbial communities built? How are their unique and specialized properties maintained? How have microbial communities evolved?

cnobile@ucmerced.edu
(209) 228-2427
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