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Immunology and Infectious Disease

Patricia LiWang
Professor
  • Biochemistry and biophysics
  • Structural biology of chemokines
  • Applications to HIV and inflammatory diseases
pliwang@ucmerced.edu
(209) 228-4568
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Jennifer O. Manilay
Associate Professor

Professor Manilay is a developmental immunologist, with research interest in the mechanisms that control cell fate decisions in the immune system. Her current topic of study is the development of T lymphocytes, important components of immune defense against pathogens.

jmanilay@ucmerced.edu
(209) 228-4175
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Katrina Hoyer
Assistant Professor

Immunological tolerance and autoimmune disease

Cellular and molecular interplay between lymphocytes and dendritic cells

khoyer2@ucmerced.edu
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Clarissa Nobile
Associate Professor

Professor Nobile's research is directed toward understanding the molecular and mechanistic basis of microbial communities. Her lab is interested in investigating how transcriptional networks underlie the regulation of gene expression during biofilm development. Much of this work is carried out in the species Candida albicans, the most prevalent fungal pathogen of humans. The lab is also beginning to study interspecies interactions between different fungal and bacterial species. Questions that the lab is currently pursuing include: How are microbial communities regulated? How are microbial communities built? How are their unique and specialized properties maintained? How have microbial communities evolved?

cnobile@ucmerced.edu
(209) 228-2427
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Kirk Jensen
Assistant Professor
  • Parasite pathogenesis and immunology
  • How Toxoplasma virulence factors manipulate host immune responses
 
kjensen5@ucmerced.edu
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Anna Beaudin
Assistant Professor

The Beaudin Lab is interested in how early life events program immunity and susceptibility to immune dysfunction across the lifespan. We approach this question by defining the developmental pathways by which hematopoietic or blood progenitors produce specialized immune cells during development, and how perturbation of fetal hematopoiesis shapes the trajectory of the immune system at the level of the hematopoietic stem cell.

Publications:

Leung GA, Cool T, Valencia CH, Worthington A, Beaudin AE, Forsberg EC. (2019) The lymphoid-associated interleukin 7 receptor (IL-7R) regulates tissue resident macrophage development. bioRxiv. Pre-print.

Boyer SW, Rajendiran S, Beaudin AE, Perez-Cunningham J, Smith-Berdan S, Martin EW, Muthuswamy PK, Cheung C, Tsang H, Landon M, Forsberg EC. (2019) Clonal and quantitative in vivo assessment of hematopoietic stem and progenitor cell differentiation. Stem Cell Reports. In press.

Beaudin AE, Boyer SW, Perez-Cunningham J, Hernandez GE, Derderian SC, Jujjavarapu C, Aaserude E, MacKenzie T, Forsberg EC. (2016) A Transient Developmental Hematopoietic Stem Cell Gives Rise to Innate-like B and T Cells. Cell Stem Cell. Dec 1;19(6):768-783. doi: 10.1016/j.stem.2016.08.013. Epub 2016 Sep 22.

 

abeaudin@ucmerced.edu
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