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David Ardell
Associate Professor

Computational biology of gene expression systems, including:

  • Structure, function, evolution and coevolution with genomes
  • Functional and evolutionary bioinformatics of RNA and proteins
  • Evolutionary and comparative genomics
(209) 228-2953
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Rudy M. Ortiz

Professor Ortiz's research focuses on the regulation of kidney function and metabolism in a variety of animal models, including seals and dolphins, with the intent that the data will have translative value to clinical medicine. These studies are conducted in collaboration with colleagues at:

  • Sonoma State University
  • University of Alaska, Fairbanks
  • University of California, Santa Cruz

His lab -  in conjunction with collaborators at Kagawa Medical University, SUNY Buffalo Medical School, and Tulane University HSC -  investigate:

  • Role of aldosterone plays in exacerbating high blood pressure
  • Effects of aldosterone antagonism and hypercholesterolemia on renal sodium regulation

Professor Ortiz is also pursuing studies that address the link between diabetes and obesity with hypertension.
From an evolutionary perspective, he is interested in the physiological mechanisms marine-adapted vertebrates use to regulate water and electrolytes during a variety of altered environmental conditions, such as prolonged food deprivation or extended fresh water exposure.
(209) 228-2964
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Nestor Oviedo
Associate Professor
  • Tissue regeneration
  • Stem cells
  • Cancer
  • Planarian biology
(209) 228-4541
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Fred Wolf
Associate Professor

The Wolf lab studies the genetic and neural circuit mechanisms for coding simple behaviors, including motivated seeking and plasticity driven by addictive drugs. We also study the regulation of DNA damage repair.


Mef2 induction of the immediate early gene Hr38/Nr4a is terminated by Sirt1 to promote ethanol tolerance. Adhikari P, Orozco D, Randhawa H, Wolf FW. Genes Brain Behav. 2019 Mar;18(3):e12486. doi: 10.1111/gbb.12486. Epub 2018 May 28.

Satiation state-dependent dopaminergic control of foraging in Drosophila. Landayan D, Feldman DS, Wolf FW. Sci Rep. 2018 Apr 10;8(1):5777. doi: 10.1038/s41598-018-24217-1.

Perineurial Barrier Glia Physically Respond to Alcohol in an Akap200-Dependent Manner to Promote Tolerance. Parkhurst SJ, Adhikari P, Navarrete JS, Legendre A, Manansala M, Wolf FW. Cell Rep. 2018 Feb 13;22(7):1647-1656. doi: 10.1016/j.celrep.2018.01.049.
(415) 370-1132
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Fabian Filipp
Assistant Professor

Systems biology of cancer metabolism:
Stable isotope fluxomics in response to nutrition, metabolic disease, and drugs; methods development in NMR spectroscopy, structural, and chemical biology; structure, dynamics, and function of human lipogenesis machinery in human cancer progression
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